Session guide · IV ketamine
What to Expect at Your First IV Ketamine Infusion
IV ketamine is given through a small drip in a clinic room while staff watch your vitals. The infusion itself is typically about 40 minutes. The whole visit runs longer, because you arrive early and rest afterward.
This is the general shape of a session, not your clinic’s protocol and not medical advice. Every clinic does things a little differently, so ask your clinic how they work.
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What to expect
Before, during, and after
This guide covers IV infusion only. IM ketamine is a shot, not a drip, and has its own guide.
01
Before
- A clinician reviews your medical history and decides with you whether IV ketamine is a fit. The infusion is usually booked as a separate visit.
- Many clinics ask for no solid food for 4 to 6 hours beforehand, and clear liquids only until 2 hours before. Your clinic will give you their rule.[1]
- Bring an eye mask, headphones, a light blanket, and loose clothing that leaves your arm easy to reach.[1]
- Arrange a ride home in advance.
- Feeling nervous the night before is normal. Mention it when you arrive.
02
During
- You sit or recline in a private treatment room while a clinician places a small IV line in your hand or arm.
- The infusion typically runs about 40 minutes.
- Staff monitor your vitals throughout. You can speak up at any time, and they can slow the drip if you are uncomfortable.[1]
- Many people feel floaty or dreamlike. Most people stay aware of their surroundings, and opening your eyes usually makes the effects feel lighter.[1]
- Nausea, feeling unsteady, and feeling detached are common. They pass as the medicine wears off, and nausea can be treated.[1]
- Ketamine is FDA-approved as an anesthetic. Using it for mental health is off-label, and your clinician should explain what that means.[2]
Sources
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