Oregon made history as the first state to offer regulated psilocybin services, launching in June 2023 under Measure 109. The Oregon Health Authority (OHA) oversees the program through its Oregon Psilocybin Services (OPS) section. As of early 2026, approximately 22–23 licensed service centers operate statewide — out of 35 approved licenses, roughly 12–13 have closed. Nearly 400 active facilitators hold licenses. The program has served an estimated 15,000–16,000 clients since launch — the largest regulated psilocybin dataset in the world. Oregon's program is a supervised service model, not healthcare: no diagnosis, prescription, or referral is required. Any adult 21 or older, from any state or country, may access services.

Program Overview

Oregon's Measure 109 program is overseen by the OHA's Oregon Psilocybin Services (OPS) section, which licenses four categories of businesses: service centers, facilitators, manufacturers, and testing laboratories. EPIC Healing Eugene opened as the nation's first licensed psilocybin service center in June 2023. By early 2026, OHA had approved 35 service center licenses, with approximately 12–13 closures leaving roughly 22–23 operational locations statewide. Almost 400 facilitators hold active licenses. The OHA Data Dashboard, mandated by SB 303, reports 1,509 clients served in Q1 2025 alone and approximately 4,577 in the first three quarters of 2025, with a cumulative total estimated at 15,000–16,000 clients. Over 37,000 psilocybin products have been sold, generating more than $1.7 million in revenue. A significant 2025 update — HB 2387, effective January 1, 2026 — allows licensed healthcare providers who also hold facilitator licenses to deliver psilocybin services without risking professional board discipline.

Who Can Access

Any adult 21 or older may participate regardless of state or country of residence — no residency requirement applies. Oregon's program is classified as a supervised service model, not healthcare, meaning no medical diagnosis, physician referral, or prescription is required. Facilitators screen clients against four absolute exclusions: (1) being under 21, (2) a personal history of active psychosis such as schizophrenia or schizoaffective disorder, (3) current suicidal or homicidal ideation, and (4) lithium use within the past 30 days. Pregnancy is not a formal legal exclusion, but virtually all centers decline to serve pregnant clients. SSRIs are not excluded — an estimated 80% of clients may be taking them, though facilitators discuss potential interactions during screening. Approximately 60% of all clients come from outside Oregon, and some Ashland centers report 80–90% out-of-state clientele.

What It Costs

Session pricing varies significantly based on the center, format, and package. Budget and equity programs: $700–$1,050 — Satya Therapeutics in Ashland offers sessions starting at $1,050 all-inclusive with the state's lowest product cost of $25 for up to 50mg psilocybin. Standard individual sessions: $1,500–$3,500 (most common range) — InnerTrek in Portland charges $1,500–$2,500. Group sessions: $850–$2,000 per person — EPIC Healing Eugene group sessions are priced around $1,800. Premium retreats: $3,500–$6,500 — Odyssey offers multi-day all-inclusive retreats in Bend and the Willamette Valley. Nonprofit sliding scale: near $0 at Bendable Therapy in Bend, Oregon's first nonprofit psilocybin center. Couples sessions are offered at centers such as Bend InnerAlchemy at $5,000 for two people. Travel adds $2,000–$3,500 for out-of-state visitors. See our full Oregon cost guide for a complete breakdown by center and format.

What to Expect

Oregon's three-session structure provides a clear pathway. Preparation is mandatory and can occur in person or virtually, typically 60–90 minutes across one to three meetings. The facilitator covers informed consent (30+ statements), a Client Bill of Rights, a safety and support plan, a mandatory transportation plan, medical history, medications, and intentions. Administration is the core experience and the only phase that must occur at a licensed service center — the sole legal venue for purchasing and consuming psilocybin. Sessions run four to eight hours depending on dosage. Clients choose from microdoses below 2.5mg, moderate doses of 2.5–25mg, or full doses up to the regulatory cap of 50mg. All products are derived exclusively from Psilocybe cubensis — dried mushrooms, extracts, chocolates, teas, and tinctures. The facilitator remains present throughout using a non-directive approach. Integration follows within 72 hours: a one-to-two-hour session to process insights. EPIC Healing Eugene offers free bimonthly group integration sessions with no limit; Odyssey provides lifetime access to monthly integration circles plus up to five free therapy sessions.

Safety Record

Oregon's safety record is exceptionally clean. Through early 2026, only about two dozen adverse events have been reported across all service centers since launch in June 2023 — none requiring hospitalization, and no product recalls. The adverse event rate stands at roughly 0.15% among the estimated 15,000–16,000 clients served. These figures represent the world's largest real-world dataset on regulated psilocybin therapy. Oregon's safety outcomes are widely cited as evidence that a well-designed regulatory framework can deliver broad access with minimal clinical risk. The OHA Data Dashboard publishes quarterly adverse event and client statistics under SB 303.

Where Centers Are Located

Over 100 cities and 25 of Oregon's 36 counties have enacted bans or moratoriums on psilocybin businesses, concentrating the industry along the western corridor. Portland has the largest concentration: InnerTrek (co-founded by Measure 109 co-creator Tom Eckert), Fractal Health, Meadow Medicine, and Lucid Cradle. Ashland has emerged as a psilocybin tourism hub with Satya Therapeutics, Omnia Group, Confluence Retreats, Aurora Healing Garden, and the Ashland Healing Center — Omnia reports roughly 80% of its clients from outside Oregon. Eugene is home to EPIC Healing Eugene (the state's first licensed center) and Mandala Journey Work. Bend offers Bendable Therapy (nonprofit), Bend InnerAlchemy, and Odyssey's retreat operations. Salem hosts The Psilocybin Center, which explicitly markets to out-of-state visitors. Multnomah County (Portland) is the top source of in-state clients, accounting for 33–43% of Oregon-resident sessions.

Insurance & Payment

No major health insurer covers psilocybin therapy in Oregon. The sole insurance workaround is Enthea, a Massachusetts-based third-party administrator offering employer- and union-sponsored coverage as a workplace benefit. In April 2025, Bendable Therapy in Bend became the first Oregon service center to accept Enthea coverage. Enthea's Oregon network has since expanded to include Odyssey, Chariot, Drop Thesis, Gather Psilocybin Services, and 7 Gates Sanctuary. Drop Thesis in Bend obtained a national provider identification (NPI) number, enabling use of health savings accounts (HSAs). The Psilocybin Access Fund, run by the Sheri Eckert Foundation, has awarded over $51,000 in grants to 33+ individuals from underserved communities, with a 2025–2026 fundraising goal of $1 million. Industry leaders expect meaningful insurance coverage to depend on federal rescheduling — the DEA forwarded a rescheduling petition in August 2025.

Frequently Asked Questions

Comparing costs by city? Session prices in Oregon range from $700 at equity programs to $6,500+ for premium retreats. See per-center pricing for Portland, Ashland, Eugene, and Bend. Browse Oregon psilocybin therapy costs →

Learn more about psilocybin therapy legality across all US states — including Oregon, the other states with active programs, and what federal rescheduling could mean for patients nationwide. Read our complete psilocybin legality guide →

Wondering when psilocybin could become an FDA-approved prescription medicine? COMPASS Pathways is targeting a late-2026 NDA submission for COMP360. Track the FDA approval timeline for psilocybin →